Metabolic effects of vitamin E and selenium

Protective effects of vitamin E and selenium on spermatogenesis in adult male rat insulin-resistant

Background & Objective: Diabetes mellitus is a metabolic disease and is a multifactorial disorder characterized by chronic hyperglycemia resulting from impaired insulin secretion and insulin factional or both. In this study, the protective role of vitamin E and sodium selenite in preventing the harmful effects of insulin resistance (diabetes type 2) on spermatogenesis was studied.   Materials &...

Effects of selenium and vitamin e supplementation on concentrations of selenium and immunoglobulins in colostrum and blood of baluchi ewes and lambs and on lamb growth

Baseline selenium status and effects of selenium and vitamin e supplementation on prostate cancer risk.

BACKGROUND The Selenium and Vitamin E Cancer Prevention Trial found no effect of selenium supplementation on prostate cancer (PCa) risk but a 17% increased risk from vitamin E supplementation. This case-cohort study investigates effects of selenium and vitamin E supplementation conditional upon baseline selenium status. METHODS There were 1739 total and 489 high-grade (Gleason 7-10) PCa cases...

Selenium and vitamin E cancer prevention trial.

Preclinical, epidemiological, and phase III data from randomized, placebo-controlled clinical trials suggest that both selenium and vitamin E have potential efficacy in prostate cancer prevention. In vitro evidence suggests that selenium and vitamin E work synergistically to cause cell-cycle arrest, induce caspase-mediated apoptosis, and act as antiandrogens in arresting clonal expansion of nas...

Selenium and Vitamin E for Lambs

N UTRITIONAL m u s c u l a r d y s t r o p h y (NMD) occurs spontaneously in lambs in many areas (Allaway and Hodgson, 1964; Hartley and Grant, 1961; and Muth, 1963) and can result in substantial economic loss to flock owners. Willman et al. (1945) demonstrated that vitamin E was effective in preventing and curing NMD. However, Muth (1955) and Hartley and Grant (1961) observed that vitamin E ha...